TY - JOUR T1 - COVID-19 Neurologic Complication with CNS Vasculitis-Like Pattern JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 1384 LP - 1387 DO - 10.3174/ajnr.A6651 VL - 41 IS - 8 AU - R. Hanafi AU - P.-A. Roger AU - B. Perin AU - G. Kuchcinski AU - N. Deleval AU - F. Dallery AU - D. Michel AU - L. Hacein-Bey AU - J.-P. Pruvo AU - O. Outteryck AU - J.-M. Constans Y1 - 2020/08/01 UR - http://www.ajnr.org/content/41/8/1384.abstract N2 - SUMMARY: Coronavirus disease 2019 (COVID-19) is a viral infection caused by the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), which spreads rapidly from person to person and manifests in most symptomatic patients as a respiratory illness, similar to prior SARS viruses. Neurologic manifestations of COVID-19 are uncommon; those so far reported include encephalopathy, stroke from large-vessel occlusion, and polyneuropathy. We report a unique neurologic complication of COVID-19 in a patient who had extensive cerebral small-vessel ischemic lesions resembling cerebral vasculitis in a characteristic combined imaging pattern of ischemia, hemorrhage, and punctuate postcontrast enhancement. Also, a characteristic lower extremity skin rash was present in our patient. Our observation lends support to the increasingly suspected mechanism of “endotheliitis” associated with this novel coronavirus.ACE2angiotensin converting enzyme 2COVID-19coronavirus disease 2019SARS-CoV-2Severe Acute Respiratory Syndrome coronavirus 2 ER -