PT  - JOURNAL ARTICLE
AU  - G.S. Young
AU  - K. Setayesh
TI  - Spin-Echo Echo-Planar Perfusion MR Imaging in the Differential Diagnosis of Solitary Enhancing Brain Lesions: Distinguishing Solitary Metastases from Primary Glioma
AID  - 10.3174/ajnr.A1239
DP  - 2009 Mar 01
TA  - American Journal of Neuroradiology
PG  - 575--577
VI  - 30
IP  - 3
4099  - http://www.ajnr.org/content/30/3/575.short
4100  - http://www.ajnr.org/content/30/3/575.full
SO  - Am. J. Neuroradiol.2009 Mar 01; 30
AB  - SUMMARY: Unlike the more widely reported gradient-echo echo-planar perfusion-weighted imaging (EPI-PWI) technique, spin-echo (SE) EPI relative cerebral blood volume maps select for blood volume in microvessels <8 μm in diameter. This first report of SE-EPI PWI for distinguishing brain metastasis from high-grade glioma demonstrated 88% sensitivity and 72% specificity in 83 patients. We discuss differences in microvessel architecture between high-grade glioma and brain metastasis that may explain the surprising success of SE-EPI in this application and may deserve further investigation.