RT Journal Article
SR Electronic
T1 Inclusion or Exclusion of Intratumoral Vessels in Relative Cerebral Blood Volume Characterization in Low-Grade Gliomas: Does It Make a Difference?
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1140
OP 1141
DO 10.3174/ajnr.A0993
VO 29
IS 6
A1 Caseiras, G. Brasil
A1 Thornton, J.S.
A1 Yousry, T.
A1 Benton, C.
A1 Rees, J.
A1 Waldman, A.D.
A1 Jäger, H.R.
YR 2008
UL http://www.ajnr.org/content/29/6/1140.abstract
AB SUMMARY: We assessed the influence of inclusion (method 1) and exclusion (method 2) of intratumoral vessels when determining maximum relative cerebral blood volume (rCBVmax) in 3 types of low-grade gliomas (LGGs): astrocytomas, oligoastrocytomas, and oligodendrogliomas. Method 1 yielded significantly higher mean rCBVmax than method 2. However, only method 2 demonstrated a significant (P = .026) association between rCBVmax and membership of a differently ranked histologic category. Exclusion of intratumoral vessels appears, therefore, preferable when determining rCBVmax in LGGs.