TY - JOUR T1 - Primary Sjögren Syndrome with Tumefactive Central Nervous System Involvement JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 1878 LP - 1879 DO - 10.3174/ajnr.A1204 VL - 29 IS - 10 AU - J. Sanahuja AU - S. Ordoñez-Palau AU - R. Begué AU - L. Brieva AU - D. Boquet Y1 - 2008/11/01 UR - http://www.ajnr.org/content/29/10/1878.abstract N2 - SUMMARY: Brain MR imaging abnormalities in primary Sjögren syndrome (pSS) are generally discrete white matter lesions. We describe a 50-year-old woman with recurrent neurologic deficits. MR imaging revealed a large brain lesion. A diagnosis of pSS was made on the basis of clinical features, positive anti-Ro and anti-La antibodies, abnormal Schirmer test findings, and salivary gland scintigraphy. The patient was treated with oral prednisone with good response. Large tumefactive brain lesions are a complication of pSS. ER -