RT Journal Article SR Electronic T1 Primary Sjögren Syndrome with Tumefactive Central Nervous System Involvement JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1878 OP 1879 DO 10.3174/ajnr.A1204 VO 29 IS 10 A1 J. Sanahuja A1 S. Ordoñez-Palau A1 R. Begué A1 L. Brieva A1 D. Boquet YR 2008 UL http://www.ajnr.org/content/29/10/1878.abstract AB SUMMARY: Brain MR imaging abnormalities in primary Sjögren syndrome (pSS) are generally discrete white matter lesions. We describe a 50-year-old woman with recurrent neurologic deficits. MR imaging revealed a large brain lesion. A diagnosis of pSS was made on the basis of clinical features, positive anti-Ro and anti-La antibodies, abnormal Schirmer test findings, and salivary gland scintigraphy. The patient was treated with oral prednisone with good response. Large tumefactive brain lesions are a complication of pSS.