PT  - JOURNAL ARTICLE
AU  - J S DeMeritt
AU  - J Pile-Spellman
AU  - H Mast
AU  - N Moohan
AU  - D C Lu
AU  - W L Young
AU  - L Hacein-Bey
AU  - J P Mohr
AU  - B M Stein
TI  - Outcome analysis of preoperative embolization with N-butyl cyanoacrylate in cerebral arteriovenous malformations.
DP  - 1995 Oct 01
TA  - American Journal of Neuroradiology
PG  - 1801--1807
VI  - 16
IP  - 9
4099  - http://www.ajnr.org/content/16/9/1801.short
4100  - http://www.ajnr.org/content/16/9/1801.full
SO  - Am. J. Neuroradiol.1995 Oct 01; 16
AB  - PURPOSE To determine the influence of preoperative N-butyl cyanoacrylate embolization on outcome in the treatment of cerebral arteriovenous malformations. METHODS Two groups were compared: 30 patients who underwent surgery and embolization versus 41 patients who underwent surgery only. Both groups were categorized by Spetzler-Martin grade and evaluated with the Glasgow Outcome Scale at various intervals. The long-term follow-up in months was, for surgery only, mean of 35 and range of 4 to 59, and for surgery and embolization, mean of 10 and range of 1 to 19). RESULTS The arteriovenous malformations in the surgery and embolization group had a larger average greatest diameter (4.2 +/- 1.5 cm versus 3.4 +/- 1.8 cm) and were of higher Spetzler-Martin grade (89% versus 68% grade III-V). No significant difference in the preoperative or immediate postoperative (less than 24 hours) Glasgow Outcome Scale was identified between the two groups. At I week after surgery, the surgery and embolization group displayed a significantly better outcome evaluation (70% versus 41% with Glasgow Outcome Scale score of 5). The long-term evaluation continued to favor the surgery and embolization patients (86% versus 66% with Glasgow Outcome Scale score of 5). CONCLUSION Preoperative N-butyl cyanoacrylate embolization improves postsurgical outcome.