RT Journal Article
SR Electronic
T1 Evaluation of DISORDER: Retrospective Image Motion Correction for Volumetric Brain MRI in a Pediatric Setting
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 774
OP 781
DO 10.3174/ajnr.A7001
VO 42
IS 4
A1 K. Vecchiato
A1 A. Egloff
A1 O. Carney
A1 A. Siddiqui
A1 E. Hughes
A1 L. Dillon
A1 K. Colford
A1 E. Green
A1 R.P.A.G. Texeira
A1 A.N. Price
A1 G. Ferrazzi
A1 J.V. Hajnal
A1 D.W. Carmichael
A1 L. Cordero-Grande
A1 J. O’Muircheartaigh
YR 2021
UL http://www.ajnr.org/content/42/4/774.abstract
AB BACKGROUND AND PURPOSE: Head motion causes image degradation in brain MR imaging examinations, negatively impacting image quality, especially in pediatric populations. Here, we used a retrospective motion correction technique in children and assessed image quality improvement for 3D MR imaging acquisitions.MATERIALS AND METHODS: We prospectively acquired brain MR imaging at 3T using 3D sequences, T1-weighted MPRAGE, T2-weighted TSE, and FLAIR in 32 unsedated children, including 7 with epilepsy (age range, 2–18 years). We implemented a novel motion correction technique through a modification of k-space data acquisition: Distributed and Incoherent Sample Orders for Reconstruction Deblurring by using Encoding Redundancy (DISORDER). For each participant and technique, we obtained 3 reconstructions as acquired (Aq), after DISORDER motion correction (Di), and Di with additional outlier rejection (DiOut). We analyzed 288 images quantitatively, measuring 2 objective no-reference image quality metrics: gradient entropy (GE) and MPRAGE white matter (WM) homogeneity. As a qualitative metric, we presented blinded and randomized images to 2 expert neuroradiologists who scored them for clinical readability.RESULTS: Both image quality metrics improved after motion correction for all modalities, and improvement correlated with the amount of intrascan motion. Neuroradiologists also considered the motion corrected images as of higher quality (Wilcoxon z = −3.164 for MPRAGE; z = −2.066 for TSE; z = −2.645 for FLAIR; all P < .05).CONCLUSIONS: Retrospective image motion correction with DISORDER increased image quality both from an objective and qualitative perspective. In 75% of sessions, at least 1 sequence was improved by this approach, indicating the benefit of this technique in unsedated children for both clinical and research environments.DISORDERDistributed and Incoherent Sample Orders for Reconstruction Deblurring by using Encoding RedundancyAqacquiredDiafter DISORDER motion correctionDiOutDi with additional outlier rejectionGEgradient entropy