PT - JOURNAL ARTICLE AU - Han, L. AU - Qiu, Y. AU - Xie, C. AU - Zhang, J. AU - Lv, X. AU - Xiong, W. AU - Wang, W. AU - Zhang, X. AU - Wu, P. TI - Atypical Teratoid/Rhabdoid Tumors in Adult Patients: CT and MR Imaging Features AID - 10.3174/ajnr.A2361 DP - 2011 Jan 01 TA - American Journal of Neuroradiology PG - 103--108 VI - 32 IP - 1 4099 - http://www.ajnr.org/content/32/1/103.short 4100 - http://www.ajnr.org/content/32/1/103.full SO - Am. J. Neuroradiol.2011 Jan 01; 32 AB - SUMMARY: Primary AT/RT is a rare highly malignant tumor of the CNS, usually occurring in children younger than 5 years of age. The objective of this study was to characterize the CT and MR imaging findings in a series of 5 adult patients with pathologically proved AT/RT. All 5 AT/RTs were supratentorial. In 2 patients who underwent nonenhanced CT, the tumors appeared isoattenuated, and 1 of the 2 tumors contained calcifications. Solid portions of the tumors on MR imaging were isointense on T1-weighted, T2-weighted, and FLAIR images, and 1 case showed restricted diffusion on DWI. The tumors also demonstrated a bandlike rim of strong enhancement surrounding a central cystic area on contrast-enhanced T1-weighted imaging. One tumor was associated with destruction of the calvaria. Although AT/RTs can have nonspecific findings, the tumors in our series were large and isointense on T1-weighted, T2-weighted, and FLAIR images with central necrosis and prominent rim enhancement. ADCapparent diffusion coefficientAT/RTatypical teratoid/rhabdoid tumorCNScentral nervous systemDWIdiffusion-weighted imagingFLAIRfluid-attenuated inversion recoveryLleftmRNAmessenger ribonucleic acidN/Anot availableNDnot depictedOSoverall survivalPNETprimitive neuroectodermal tumorPRpartial resectionRrightTRtotal resection