RT Journal Article
SR Electronic
T1 Hydrocephalus in Patients with Neurofibromatosis Type 1: MR Imaging Findings and the Outcome of Endoscopic Third Ventriculostomy
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 643
OP 646
DO 10.3174/ajnr.A2357
VO 32
IS 4
A1 A. Dinçer
A1 U. Yener
A1 M.M. Özek
YR 2011
UL http://www.ajnr.org/content/32/4/643.abstract
AB SUMMARY: Although hydrocephalus associated with NF-1 is not rare, up to now the MR imaging findings in these patients and the role of ETV in the treatment of hydrocephalus associated with NF-1 have not been investigated thoroughly. We present the MR imaging findings of hydrocephalus associated with NF-1 in 7 of 54 patients with NF-1. Although the types of obstruction were various, including aqueductal web, superior velum medullary synechia, periaqueductal/tectal hamartomas, cerebellar and pontine tegmentum hamartomas, brain stem glioma, or a combination, the presence of hamartomas was a consistent finding in patients with NF-1 with hydrocephalus. In 5 cases, 8 ETV procedures were performed and followed for up to 53 months. All children treated with ETV were shunt-free at their most recent examinations. ETV may be the primary procedure for the treatment of hydrocephalus associated with NF-1, regardless of the cause and the level of the obstruction. cine PCcine phase-contrastCNScentral nervous systemETVendoscopic third ventriculostomy3D-CISS3D constructive interference in steady stateNF-1neurofibromatosis type 1TSEturbo spin-echo