RT Journal Article
SR Electronic
T1 Platelet Aggregation in Intracranial Stents May Mimic In-Stent Restenosis
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 496
OP 497
DO 10.3174/ajnr.A1778
VO 31
IS 3
A1 Mazighi, M.
A1 Maurice, J.P. Saint
A1 Bresson, D.
A1 Szatmary, Z.
A1 Houdart, E.
YR 2010
UL http://www.ajnr.org/content/31/3/496.abstract
AB SUMMARY: We report the case of an early ISR that was due to platelet aggregation despite correct observance of a standard antiplatelet regimen. Biologic testing showed clopidogrel inefficiency, and ISR disappeared on angiography after a loading dose of clopidogrel. This result suggested that the arterial lumen reduction was due to platelet aggregation rather than in-stent myointimal hyperplasia. This observation emphasizes the importance of verifying the efficacy of clopidogrel before placing a stent. APanteroposteriorCTACT angiographyISRin-stent restenosisMCAmiddle cerebral arteryTCDtranscranial DopplerTIAtransient ischemic attackVASPvasodilator-stimulated phosphoprotein.