PT - JOURNAL ARTICLE AU - K.J. Brown AU - V. Jewells AU - H. Herfarth AU - M. Castillo TI - White Matter Lesions Suggestive of Amyotrophic Lateral Sclerosis Attributed to Celiac Disease AID - 10.3174/ajnr.A1826 DP - 2010 May 01 TA - American Journal of Neuroradiology PG - 880--881 VI - 31 IP - 5 4099 - http://www.ajnr.org/content/31/5/880.short 4100 - http://www.ajnr.org/content/31/5/880.full SO - Am. J. Neuroradiol.2010 May 01; 31 AB - SUMMARY: CD is an autoimmune-mediated disorder of the gastrointestinal tract. Initial symptom presentation is variable and can include neurologic manifestations that may comprise ataxia, neuropathy, dizziness, epilepsy, and cortical calcifications rather than gastrointestinal-hindering diagnosis and management. We present a case of a young man with progressive neurologic symptoms and brain MR imaging findings worrisome for ALS. During the diagnostic work-up, endomysium antibodies were discovered, and CD was confirmed by upper gastrointestinal endoscopy with duodenal biopsies. MR imaging findings suggestive of ALS improved after gluten-free diet institution. ALSamyotrophic lateral sclerosisCDceliac diseaseFLAIRfluid-attenuated inversion recoveryIgAimmunoglobulin A