AVM characteristics and factors associated with obliteration after repeat GKRS
Total No. (n = 25) | Obliteration (n = 16) (64%) | Incomplete Obliteration (n = 9) (36%) | P Value | |||
---|---|---|---|---|---|---|
Rupture (No.) (%) | 18 (72) | 11 (69) | 7 (78) | 1.0 | ||
Spetzler-Martin grade (No.) (%) | .62 | |||||
I/II | 5 (20) | 4 (25) | 1 (11) | |||
III/IV/V | 20 (80) | 12 (75) | 8 (89) | |||
Median AVM score (range) | 1.17 (0.320–2.20) | 1.25 (0.675–2.20) | 0.86 (0.320–1.95) | .12 | ||
Deep drainage (No.) (%) | 17 (72) | 10 (63) | 7 (78) | .66 | ||
Location (No.) (%) | .85 | |||||
Lobar | 13 (52) | 9 (57) | 4 (44) | |||
Thalamus/basal ganglia/brainstem | 10 (40) | 6 (38) | 4 (33) | |||
Cerebellum | 2 (12) | 1 (6.3) | 1 (11) | |||
Eloquent cortex of adjacent brain (No.) (%) | 17 (68) | 11 (69) | 6 (67) | 1.0 | ||
Prior embolization (No.) (%) | 6 (25) | 4 (25) | 2 (22) | 1.0 | ||
Median AVM volume at initial GKRS (range) (mL) | 3.70 (0.03–31.3) | 4.90 (0.06–31.3) | 3.5 (0.42–12.3) | .80 | ||
Median AVM volume at repeat GKRS (range) (mL) | 0.77 (0.048–9.2) | 0.59 (0.054–9.2) | 0.77 (0.048–4.1) | .93 | ||
Median margin dose (range) (Gy) | 18 (14–20) | 20 (14–20) | 18 (16–20) | .36 | ||
>50% Reduction in volume after initial GKRS (No.) (%) | 19 (76) | 12 (75) | 7 (77.8) | 1.0 |