Patient characteristics in the derivation data and in the internal and external test dataa
| Characteristic | Derivation Set (n = 329) | Internal Test Set (n = 170) | External Test Set (n = 83) |
|---|---|---|---|
| Age (yr)b | 69 (59–78) | 68 (59–79) | 71 (63–79) |
| Male | 173 (52.6) | 89 (52.4) | 43 (51.8) |
| Race | |||
| White | 261 (79.3) | 142 (83.5) | NA |
| Asian | 26 (7.9) | 10 (5.9) | |
| African American | 35 (10.6) | 14 (8.2) | |
| Other | 7 (2.1) | 4 (2.4) | |
| Onset-to-CT timeb | 160 (82–268) | 154 (79–284) | 120 (89–184) |
| Baseline NIHSS score b | 17 (12–21) | 16 (13–20) | 9 (5–15) |
| ASPECTSb | 8 (7–9) | 8 (7–9) | 10 (8–10) |
| Hypertension | 222 (67.5) | 127 (74.7) | 49 (59.0) |
| Hyperlipidemia | 140 (42.6) | 79 (46.5) | NA |
| Diabetes | 70 (21.3) | 36 (21.2) | 9 (10.8) |
| IV alteplase | 193 (58.7) | 99 (58.2) | 66 (79.5) |
| IV nerinetide | 155 (47.1) | 87 (51.2) | 0 |
| Occlusion site | |||
| ICA | 71 (21.6) | 39 (23.0) | 8 (9.6) |
| M1, MCA | 248 (75.4) | 125 (73.5) | 26 (31.3) |
| M2, MCA | 10 (3.0) | 6 (3.5) | 10 (12.1) |
| M3/M4, MCA | 0 | 0 | 13 (15.7) |
| ACA (A2/A3) | 0 | 0 | 3 (3.6) |
| PCA (P2) | 0 | 0 | 2 (2.4) |
| No occlusion | 0 | 0 | 21 (25.3) |