Association of measures of continuous imaging features with variant histone H3–altered tumors
| Imaging Metric | H3-3A | H3C2/3 | P Valuea | ||
|---|---|---|---|---|---|
| No. | Median (Range) | No. | Median (Range) | ||
| ADC total (×10–6 mm2/s) | |||||
| Mean | 46 | 1227.51 (538.06–1710.88) | 9 | 1586.56 (1224.37–1797.58) | .001 |
| Median | 46 | 1185 (532–1755) | 9 | 1654 (1215–1842) | .001 |
| Mode | 46 | 1168.14 (450.92–1902.53) | 9 | 1703.88 (1263.52–1961.24) | .001 |
| Skewness | 38 | 0.91 (−0.49–2.16) | 9 | –0.20 (−0.89–0.88) | .003 |
| Kurtosis | 38 | 1.57 (−0.60–9.71) | 9 | 0.40 (−0.78–1.79) | .002 |
| ADC_enhancement (×10–6 mm2/s) | |||||
| Mean | 33 | 1138.81 (689.44–1509.96) | 7 | 1390.54 (1033.58–1898.26) | .004 |
| Median | 33 | 1085 (667–1532) | 7 | 1364 (995–1890) | .003 |
| Mode | 33 | 1012.56 (577.86–1617.56) | 7 | 1393.38 (966.31–1746.86) | .002 |
| Skewness | 31 | 1.27 (−0.56–2.82) | 7 | 0.52 (−0.71–2.61) | .1 |
| Kurtosis | 31 | 2.08 (−0.94–13.03) | 7 | 0.85 (−0.84–9.09) | .3 |
| FLAIR/T2/T1 PG volume (×103 mm3) | |||||
| FLAIR/T2 | 44 | 35.75 (7.97–77.53) | 10 | 41.10 (22.84–77.57) | .2 |
| Enhancing | 32 | 1.90 (0.07–14.10) | 9 | 5.04 (0.04–8.25) | .6 |
↵a Wilcoxon rank-sum test.