Toxicity Association | Total No. Pts with PRES | Patients with PRES and Hemorrhage | |||
---|---|---|---|---|---|
No. Pts with Hemorrhage | Hemorrhage Subtypes (No. Pts) | ||||
Minute | Sulcal | Hematoma | |||
Immunosuppression‡ | 50 | 11 | 5 | 4 | 3 |
Solid-organ transplant | 34 | 4 | 4 (1D) | 1 | 0 |
Allo-BMT | 15 | 7 | 1 (1D) | 3 (1D) | 3 (2D) |
Other† | 1 | 0 | 0 | 0 | 0 |
Infection/sepsis/shock | 52 | 6 | 4 | 1 | 4 (1D) |
Autoimmune | 12 | 2 | 2* | 0 | 2* |
Chemotherapy | 10 | 1 | 1 | 0 | 0 |
Eclampsia | 18 | 1 | 0 | 1 | 1 |
Unknown | 9 | 2 | 0 | 1 | 1 |
Total | 151 | 23 | 12 | 7 | 11 |
Note:—D indicates that the patient died.
* A single patient with autoimmune disease and both minute hemorrhage and focal hematoma who sustained a permanent deficit (homonymous hemianopsia, hemiparesis, and facial droop).
† A single patient with psoriasis on cyclosporine.
‡ Transplant, on cyclosporine, or tacrolimus (FK-506).