Normalized volumes and asymmetry ratio of the right and left piriform-cortical amygdala in control subjects and patients groups and subgroups
| Group | Right PCA | Left PCA | Δ PCA | |
|---|---|---|---|---|
| Controls | (n = 23) | 530 ± 59 (422–644) | 512 ± 60 (406–610) | 7.2 ± 4.1 |
| Right TLE | All Patients (n = 18) | 436 ± 71 (367–585)*** | 526 ± 59 (408–612) | 19.3 ± 12.6*** |
| HS Patients (n = 8) | 384 ± 28 (367–430)***°° | 508 ± 59 (408–607) | 27.1 ± 14.4*** | |
| Without HS (n = 10) | 476 ± 69 (377–585) | 541 ± 58 (461–612) | 13.0 ± 6.3* | |
| Left TLE | All Patients (n = 21) | 512 ± 70 (364–605) | 427 ± 68 (307–506)**€€€ | 19.2 ± 16.0* |
| HS Patients (n = 11) | 492 ± 83 (364–603) | 388 ± 61 (307–488)***¥¥ | 24.0 ± 18.0* | |
| Without HS (n = 10) | 535 ± 45 (458–605) | 470 ± 47 (375–509) | 13.9 ± 12.4 |
All volumes are presented as mean ± one standard deviation of the mean (range) and given in mm3. Asymmetry ratios (Δ) are presented as mean ± one standard deviation of the mean (range) and given in percentages. Nonparametric analyses with the Bonferroni correction were used to compare means over the study groups and to determine differences between the groups.
* P < .05,
** P < .01,
*** P < .001 compared to controls.
P < .01 compared to left TLE patients,€€€ P < .001 compared to right TLE patients,
°° P < .01 compared to right TLE patients without HS,
¥¥ P < .01 compared to left TLE patients without HS. HS indicates hippocampal sclerosis; PCA, piriform-cortical amygdala; TLE, temporal lobe epilepsy.