TABLE 3:

Location of MTR decrease in patients with CISSMS compared with control subjects

Cluster No.	k Value	Corrected P Value	t Value	X	Y	Z	Location
1	142	.012	6.70	0	−42	21	CC splenium
2	2112	<.001	6.68	−2	−11	19	CC genu
			6.41	−6	−27	7	Left thalamus
			6.23	6	−17	16	Right fornix
			5.93	0	−6	24	CC body
			5.89	8	18	3	Right caudate
			5.66	−8	16	10	Left caudate
			5.31	22	−16	32	Right OF
			5.30	28	−30	24	Right parietal WM
			5.21	8	−27	11	Right thalamus
			5.17	14	−10	34	Right cingulum
3	50	.040	6.22	36	−17	8	Right insula
4	39	.035	5.86	36	17	−3	Right insula
			4.30	38	6	−4	External capsule
5	55	.009	5.69	−24	37	46	Left BA8
6	236	<.001	5.12	28	−37	6	Right optica radiata
			5.08	38	−37	6	Right ILF
			4.64	34	−44	19	Right SLF
7	34	.049	4.89	−16	−14	36	Left cingulum

Note.—CC indicates corpus callosum; OF, occipitofrontal fascicles; WM, white matter.