Case Material
| Case No. | Age*/Sex | Primary CNS Neoplasm Or Disease | Age at RT (years) | RT and Dose | Latency Interval (years) | Clinical Presentation | Location of CM’s | Number of CM’s | Treatment of CM’s | Associated Findings |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 18/F | Posterior fossaMedulloblastoma | 3 | Craniospinal RT54 Gy (T)36 Gy (CS) | 15 | Incidental | Lt temporal lobe/Intraventricular | 1 | Observation | Meningioma Scalp DFS Panhypopitutarism |
| Rt cerebellum | 1 | Observation | ||||||||
| 2 | 6/M | Posterior fossaEpendymoma | 3 | Involved field RT50.4 Gy | 3 | Incidental (Subsequent asymptomatic Hemorrhage) | Lt cerebellumRt cerebellumRt temporal lobe | 121 | SurgeryObservationObservation | TH & GH Deficiency |
| 3 | 34/M | Posterior fossaMedulloblastoma | 3 | Craniospinal RT54 Gy (T) 36 Gy (CS) | 31 | Incidental | Lt frontal lobe | 1 | Observation | Meningioma |
| 4 | 21/M | Supra-sellarGerminoma | 13 | Craniospinal RT50.4 Gy (T)36 Gy (CS) | 8 | Incidental (Subsequent asymptomatic hemorrhage) | Rt fronto-parietal lobe | 1 | Surgery | - |
| 5 | 57/F | Cushing’s Disease | 16 | Cobalt RT Unknown dose | 41 | Incidental | Rt frontal lobe | 1 | Observation | Panhypopitutarism |
Note.—Age* indicates Age at the time of diagnosis of cavernomas; RT, Radiation therapy; T, Total Dose; CS, Craniospinal Dose; CM’s, cavernous malformations; DFS, Dermatofibrosarcoma; TH, Thyroid hormones; GH, Growth hormone.