Summary of slope and intercept parameters derived from linear regression analysis of absolute differences of s, the fractional residual lumen, versus mean from published data
| Study | Slope | Intercept | SD |
|---|---|---|---|
| Eliasziw et al, 1994: Fig 5 (upper) (6) | 0.016 | 0.11 | 0.12 |
| Eliasziw et al, 1994: Fig 5 (lower) (6) | 0.077 | 0.047 | 0.08 |
| Stapf et al, 2000: Table 1 (ECST) (15) | 0.000 | 0.044 | 0.04 |
| Stapf et al, 2000: Table 1 (NASCET) (15) | −0.003 | 0.047 | 0.05 |
| Young et al, 1996: Fig 3 (12) | 0.034 | 0.093 | 0.11 |
| Young et al, 1996: Fig 4 (12) | 0.024 | 0.062 | 0.07 |
| Young et al, 1996: Fig 5 (12) | 0.017 | 0.079 | 0.08 |
| Average | 0.023 | 0.072 | 0.08 |
| Rothwell et al, 1994 (8) | 0.16 | 0.022 | 0.08 |
| Simulation | 0.036 | 0.062 | 0.08 |
The SD is the value predicted by the regression analysis at s = 0.4 (60% diameter stenosis). For Rothwell et al (8), this represents linear regression of SD data pooled by decile obtained from Figure 6 of Rothwell et al (14). The average SD (0.08) was obtained from the unweighted average of the variance for each of the studies above this line. The 95% CI for the average is 0.05–0.11. For the simulation, the values in the table reflect the fit after iteration to match the variance of the simulation to the mean variance for the published data.