Comparison of baseline characteristics for patients with near occlusion (% of group)
| Patient Characteristic | NASCET ITT (N = 137) | ECST ITT (N = 125) | P Value | Medical ITT (N = 114) | Medical On- Treatment* (N = 78) |
|---|---|---|---|---|---|
| Assigned to carotid endarterectomy | 51.1 | 62.4 | — | — | |
| Age ≥65 y† | 53.3 | 36.8 | 0.007 | 48.2 | 44.9 |
| Male sex | 79.6 | 82.4 | 0.56 | 78.1 | 82.1 |
| Hemispheric TIA or stroke in the past 180 d‡ | 67.1 | 72.0 | 0.39 | 74.6 | 82.0 |
| Last ischemic event to randomization >4 wk | 43.1 | 60.0 | 0.006 | 54.4 | 55.1 |
| History of: | |||||
| Treated hypertension | 46.7 | 43.2 | 0.57 | 45.6 | 44.9 |
| Diabetes mellitus | 16.8 | 9.6 | 0.09 | 18.4 | 19.2 |
| Myocardial infarction or angina | 32.1 | 19.2 | 0.02 | 28.9 | 24.4 |
| Intermittent claudication | 12.4 | 18.4 | 0.18 | 14.9 | 15.4 |
| Hyperlipidemia | 26.3 | 10.4 | 0.001 | 21.9 | 17.9 |
| Smoking in the past year | 48.2 | 64.8 | 0.007 | 55.3 | 53.8 |
| Irregular/ulcerated carotid artery plaque§ | 38.7 | 73.6 | <0.001 | 55.3 | 59.0 |
Note.—ITT indicates intention-to-treat; TIA, transient ischemic attack.
* Medically treated patients who remained on medical therapy for the duration of the trial. There were no statistically significant different patient characteristics in comparison to the Medical ITT.
† Mean age of patients: NASCET ITT, 64.0 years; ECST ITT, 61.4 years; P value = .01. Mean age of patients: Medical ITT, 63.3 years; Medical On-Treatment, 63.6 years.
‡ Hemispheric, not ocular only events.
§ Ipsilateral to the territory of the last ischemic event.