Treatment variables of patients with acute ischemic stroke treated with IA thrombolysis
| Variable | Age <80 years (n = 81) | Age ≥80 years (n = 33) |
|---|---|---|
| BP peak, intraprocedural, mm Hg, mean ± SD | ||
| Systolic | 170 ± 21 | 180 ± 23 |
| Diastolic | 92 ± 17 | 92 ± 16 |
| Time from onset to start of IA infusion, min, mean ± SD | 261 ± 150 | 257 ± 125 |
| Time from onset to start of IA infusion 0–180 minutes, % | 22% | 12% |
| Time from onset to start of IA infusion 181–360 minutes, % | 70% | 67% |
| Time from onset to start of IA infusion >360 minutes, % | 8% | 21% |
| Time from onset to end of procedure, min, mean ± SD | 334 ± 150 | 336 ± 128 |
| Treatment regimen, n (%) | ||
| IA urokinase alone | 33 (41%) | 15 (45%) |
| IA tPA alone | 44 (54%) | 15 (45%) |
| IV/IA tPA | 4 (5%) | 3 (10%) |
| Total IA tPA dose, mg, mean ± SD* | 16.8 ± 10.5 | 17.2 ± 10.0 |
Note:—IA indicates intra-arterial; IV, intravenous; tPA, tissue plasminogen activator; BP, blood pressure.
* In patients receiving IA tPA