Relationship between changes in extent of bone marrow edema (BME) in treated vertebral compression fractures (VCF) and corresponding decreases in visual analog score (VAS) for pain and use of analgesics in the 3 follow-up intervals after percutaneous vertebroplasty (PV) in 31 patients (subgroup A)
Change in BME Extent | Follow-up Interval after PV | |||||
---|---|---|---|---|---|---|
0–3 mo | 3–6 mo | 6–12 mo | ||||
Decrease Mean VAS | Decrease Analgesic Use | Decrease Mean VAS | Decrease Analgesic Use | Decrease Mean VAS | Decrease Analgesic Use | |
Decrease in BME | 6.3 | 86% | 0.4% | 0% | 0.7% | 14% |
Similar BME | 6.0 | 67% | 0.2 | 15% | 0.1 | 4% |
Regression coefficient | 1.3 | 0.8 | 0.2 | 0.2 | 0.6 | 0.6 |
95% confidence interval | −4.4–1.7 | −2.0–0.5 | −1.0–0.7 | −0.9–0.8 | −1.8–0.5 | −1.8–0.5 |
BME absent | 6.3 | 89% | 0.2 | 14% | 0.2 | 5% |
BME present | 6.0 | 82% | 0.3 | 6% | 0.4 | 8% |
Regression coefficient | 0.2 | 0.5 | 0.1 | 0.02 | 0.1 | 0.1 |
95% Confidence interval | −1.9–2.2 | −1.3–0.4 | −0.9–0.07 | −0.9–0.8 | −1.1–0.9 | −1.1–0.9 |