Concentration ratios involving Lac, NAA, Cho, and Cr
| Concentration Ratio | Control Group (n = 10) | Neonatal Encephalopathy Infants (n = 17) | P Values | |||
|---|---|---|---|---|---|---|
| Normal/Mild Outcome (n = 10) | Severe/Fatal Outcome (n = 7) | Control Versus Normal/Mild Outcome | Control Versus Severe/Fatal Outcome | Normal/Mild Outcome Versus Severe/Fatal Outcome | ||
| [Lac]/[Cr] | 0.26 (0.09) | 0.33 (0.11) | 0.68 (0.28–2.32) | .12 | .11 | .26 |
| [Lac]/[NAA] | 0.31 (0.12) | 0.39 (0.13) | 0.69 (0.38–4.12) | .19 | .05* | .09 |
| [Lac]/[Cho] | 0.66 (0.26) | 0.83 (0.30) | 2.33 (0.73–4.81) | .19 | .06 | .22 |
| [NAA]/[Cr] | 0.86 (0.15) | 0.81 (0.73–0.94) | 0.72 (0.14) | .79 | .08 | .09 |
| [NAA]/[Cho] | 2.12 (0.28) | 2.14 (0.34) | 1.90 (1.35–2.08) | .89 | .16 | .34 |
| [Cho]/[Cr] | 0.41 (0.08) | 0.42 (0.11) | 0.40 (0.33–0.43) | .82 | .81 | .88 |
Note:—Lac indicates lactate; NAA, N-acetylaspartate; Cho, choline; Cr, creatine.
* Denotes statistically significant differences between the groups. Values are mean (SD) and median (interquartile range) as appropriate.