Presence and distribution of the citrulline peak in patients with MS according to the VOI site revealed by 1H-MR Spectroscopy
| Patient No. | Citrulline Peak on 1H-MR Spectroscopy | ||
|---|---|---|---|
| NAWM | CDL | EDL | |
| 1 | + | – | na |
| 2 | na | – | – |
| 3 | na | – | na |
| 4 | + | – | – |
| 5 | – | na | na |
| 6 | + | + | na |
| 7 | + | + | na |
| 8 | – | – | na |
| 9 | + | – | na |
| 10 | – | – | + |
| 11 | – | – | na |
| 12 | – | + | – |
| 13 | + | – | na |
| 14 | – | – | – |
| 15 | – | – | – |
| 16 | – | – | na |
| 17 | – | na | na |
| 18 | + | + | – |
| 19 | – | – | na |
| 20 | – | – | na |
| 21 | + | + | – |
| 22 | – | + | na |
| 23 | – | – | na |
| 24 | – | + | na |
| 25 | – | – | na |
| 26 | – | – | na |
| 27 | – | – | na |
Note:—na indicates that MR spectroscopy could not be performed due to absence of such a VOI site; +, present; –, absent; MS, multiple sclerosis; VOI, voxel of interest; NAWM, normal-appearing white matter; CDL, chronic demyelinating lesions; EDL, enhanced demyelinating lesions.