Manifestations of Lyme Borreliosis | ||
---|---|---|
LNB | American LNB | European LNB |
Subspecies | B burgdorferi sensu stricto | B garinii > B afzelii |
LNB/LD | <10% | >35% |
Painful radiculitis | <10% | >50% |
Aseptic meningitis at presentation | Majority | Minority |
Intrathecal antibodies | Minority | >50% |
Cranial neuropathy | VII, rarely others | VII and others |
Chronic encephalomyeloradiculitis | <0.1% | Unusual, <3% |
Erythema migrans | Common, <5 cm erythematous patch at the site of tick bite | Uncommon |
Chronic skin manifestations | Never | 10% Acrodermatitis chronica atrophicans: chronic extensor surface discoloration |
± Swelling | ||
± Associated peripheral neuropathy | ||
Associated Lyme arthritis | Common, pauciarticular; knees ∼50%, weeks-to-months postinfection | Rare |
Carditis | Heart block, transient possible perimyocarditis | Rare |
Note:—LD indicates Lyme disease; LNB, Lyme neuroborreliosis.
* Adapted from Pachner and Steiner,8 Hengge et al,16 and Stanek.22