Univariable ANOVA of clinical variables as predictors of platelet inhibition
| Platelet Inhibition (%) | Parameter Estimate (b) | P Value | |
|---|---|---|---|
| Demographics | |||
| Age (years) | – | −0.25 | .303 |
| Age groups (No.) | −15.8 | .031 | |
| <55 years (21) | 53.0 | ||
| >55 years (34) | 37.2 | ||
| Sex (No.) | −2.3 | .755 | |
| Women (34) | 44.1 | ||
| Men (21) | 41.8 | ||
| Medical history | |||
| Hypertension (No.) | −13.1 | .077 | |
| No (34) | 48.2 | ||
| Yes (21) | 35.1 | ||
| Diabetes (No.) | −24.0 | .036 | |
| No (49) | 45.8 | ||
| Yes (6) | 21.8 | ||
| Hypercholesterolemia (No.) | −11.8 | .153 | |
| No (41) | 46.2 | ||
| Yes (14) | 34.4 | ||
| Coronary artery disease (No.) | 2.7 | .789 | |
| No (47) | 43.6 | ||
| Yes (8) | 40.9 | ||
| Prior stroke (No.) | 6.7 | .414 | |
| No (40) | 41.4 | ||
| Yes (15) | 48.1 | ||
| Prior TIA (No.) | −11.6 | .288 | |
| No (48) | 44.7 | ||
| Yes (7) | 33.1 | ||
| Statin use (No.) | −13.9 | .085 | |
| No (40) | 47.0 | ||
| Yes (15) | 33.1 | ||
| ACE-I use (No.) | −13.5 | .199 | |
| No (48) | 45.0 | ||
| Yes (7) | 31.5 | ||
| Beta blocker use (No.) | −4.0 | .684 | |
| No (46) | 43.9 | ||
| Yes (9) | 39.9 | ||
| Ca-channel blocker use (No.) | 6.9 | .671 | |
| No (52) | 42.8 | ||
| Yes (3) | 49.7 | ||
| Diuretic use (No.) | −5.1 | .471 | |
| No (49) | 44.1 | ||
| Yes (6) | 35.7 | ||
| Aspirin use (No.) | −8.4 | .562 | |
| No (3) | 52.0 | ||
| Yes (52) | 47.7 | ||
| Timing of clopidogrel initiation (No.) | −0.8 | .889 | |
| <3 days (14) | 43.2 | ||
| 3–7 days (25) | 44.9 | ||
| >7 days (16) | 40.7 | ||
| Laboratory values | |||
| Creatinine (mg/dL) | – | −22.7 | .175 |
| Glucose (mg/dL) | – | −0.21 | .035 |
| Hemoglobin (g/dL) | – | −0.55 | .825 |
| Platelet count (1,000/μL) | – | 0.07 | .190 |
| Angiographic features | |||
| Stent indication (No.) | −6.0 | .490 | |
| Aneurysm (42) | 45.1 | ||
| Stenosis (13) | 39.1 | ||
| Stent location (No.) | −14.7 | .029 | |
| MCA/ACA/PcomA (19) | 53.4 | ||
| Other (36) | 38.7 | ||
| Outcomes | |||
| Re-stenosis at 6 months (No.) | 7.8 | .774 | |
| No (54) | 43.1 | ||
| Yes (1) | 50.9 | ||
| Stroke or TIA at 6 months (No.) | −4.8 | .806 | |
| No (53) | 43.4 | ||
| Yes (2) | 38.6 |
Note:— –indicates data not available; TIA, transient ischemic attack; Ca, calcium; MCA, middle cerebral artery; ACA, anterior cerebral artery; PcomA, posterior communicating artery; No., number.