Anatomic distribution of brain white matter regions with reduced FA
| Variable | No. of Regions with Reduced FA | |
|---|---|---|
| All Patients (n = 21), n (%) | Per Patient, Mean ± SD | |
| Cerebral lobar white matter | 118 (61.8)* | 5.6 ± 2.6* |
| Centrum semiovale | 27 (14.1) | 1.3 ± 1.3 |
| Frontal lobe | 42 (21.9) | 2.0 ± 1.3 |
| Parietal lobe | 31 (16.1) | 1.5 ± 1.4 |
| Temporal lobe | 28 (14.6) | 1.3 ± 1.1 |
| Occipital lobe | 4 (2.1) | 0.2 ± 0.4 |
| Cingulum/corpus callosum | 45 (23.6) | 2.1 ± 1.0 |
| Internal capsules | 11 (5.7) | 0.5 ± 0.7 |
| Anterior limb | 2 (1.0) | 0.1 ± 1.3 |
| Posterior limb | 9 (4.7) | 0.4 ± 0.5 |
| Mesencephalon | 7 (3.7) | 0.3 ± 0.6 |
| Brain stem | 4 (2.1) | 0.2 ± 0.4 |
| Cerebellum | 6 (3.1) | 0.3 ± 0.5 |
| Total | 191 (100) | 9.1 ± 3.2 |
Note:—FA indicates fractional anisotropy.
* The values of the 5 sublocations in cerebral lobar white matter (ie, centrum semiovale to occipital lobe) add up to more than the value for cerebral lobar white matter as a whole because a given region with reduced FA could be scored in more than 1 sublocation.