Table 2:

Peaks for significant clusters of decreased FA in patients with PD*

PD Versus ControlsHemisphereBrodmann AreaMNI CoordinatesZ-Score
xyz
Medial frontal cortex
    SMAL6−414463.3
    Pre-SMAR8426522.79
R6618602.83
    Rostral medial frontal gyrusR9646362.97
Cingulate cortex
    Anterior cingulate gyrus240−6464.12
L24−634463.41
32014383.00
L32−826283.11
    Rostral cingulate gyrusR241030183.00
L32−84422.82
L9−846223.18
Dorsolateral prefrontal cortex
    Superior frontal gyrusR91844324.14
    Middle frontal gyrusR462842143.50
    Inferior frontal gyrusR46423462.93
    Frontal pole
    Middle frontal gyrusR102046103.17
L10−284283.06
WM bundles
    Superior longitudinal fasciculusR3026163.09
    Corpus callosumL−1634103.02
  • Note:—SMA indicates supplementary motor area; MNI, Montreal Neurologic Institute.

  • * All significant maxima were part of a single large cluster, including 3927 voxels.