Sensitivity and specificity of CTASI compared with NCCT to identify subsequent infarction on follow-up images in individual pc-ASPECTS regions
| Pc-ASPECTS Region | CTASI | NCCT | ||
|---|---|---|---|---|
| Sensitivity (95% CI) | Specificity (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) | |
| All pc-ASPECTS regions | 35 (29–43)* | 98 (95–99) | 18 (13–25) | 94 (89–96) |
| Categorization by recanalization status | ||||
| Recanalization ≤ 24 hours | 34 (25–44) | 96 (90–99) | 18 (12–28) | 93 (86–97) |
| No recanalization ≤ 24 hours | 58 (39–74)* | 100 (91–100) | 15 (6–33) | 86 (76–93) |
| Recanalization status not assessed | 25 (14–40) | 99 (91–100) | 21 (11–35) | 91 (84–95) |
| Individual regions | ||||
| Midbrain | 59 (41–76) | 96 (85–99) | 26 (14–45) | 98 (88–100) |
| Pons | 38 (23–56)* | 96 (84–99) | 6 (1–22) | 98 (87–100) |
| Thalamus | 37 (21–56) | 98 (88–100) | 17 (6–35) | 88 (75–95) |
| Cerebellum | 32 (20–47) | 100 (86–100) | 26 (15–41) | 100 (85–100) |
| PCA | 17 (7–35) | 100 (90–100) | 18 (7–35) | 87 (73–95) |
Note:—Pc-ASPECTS indicates posterior circulation Acute Stroke Prognosis Early CT Score; CTASI, CT angiography source images; NCCT; noncontrast CT; PCA, posterior cerebral artery.
* Indicates results where 95% confidence intervals for CTASI and NCCT do not overlap.