Study | Year of Publication | Contrast Medium | No. of Subjects | Criterion for CIN | Outcome |
---|---|---|---|---|---|
Barrett23 | 2006 | Iopamidol, Iodixanol | 153 | increase ≥0.5 mg/dL in SCr | CIN in 3% (2 subjects) of iodixanol-group |
Becker37 | 2005 | Iodixanol | 100 | >0.5 mg/dL increase in SCr | CIN in 9% |
Kolehmainen25 | 1998 | Iobitridol, iodixanol | 50 | ≥0.5 mg/dL increase in SCr | CIN in 4 of 25 subjects in each group |
Tepel32 | 2000 | Iopromide | 83 | ≥0.5 mg/dL increase in SCr | CIN in 21% without NAC |
Carraro24 | 1998 | Iopromide, iodixanol | 64 | ≥50% increase in SCr | CIN in no subject who received LOCM and in 3% (2/32) with IOCM |
Note:—SCr indicates serum creatinine; CIN, contrast-induced nephropathy; LOCM, low osmolar contrast medium; IOCM, iso-osmolal contrast medium; NAC, N-Acetylcystein.