Sensitivity, specificity, PPV, and NPV of ITSSs for differentiating specific pathologic groups of SELs
| Differential Diagnosis | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|
| GBM vs metastasis | 84.0% | 60.0% | 77.8% | 69.2% |
| HGG vs metastasis | 70.0% | 60.0% | 77.8% | 50.0% |
| HGG vs lymphoma | 86.7% | 100.0% | 100.0% | 63.6% |
| HGG vs nontumor | 86.7% | 100.0% | 100.0% | 75.0% |
Note:—HGG indicates high-grade glioma; PPV, positive predictive value; NPV, negative predictive value.