Table 2:

DTI and fiber tracking characteristics of the corpus callosum in control subjects and patients with TBI*

Control Subjects (n = 10)Mild TBI (n = 24)Moderate TBI (n = 9)Severe TBI (n = 6)
Genu
    FA0.74 (0.70–0.78)0.66 (0.63–0.69)0.56 (0.47–0.65)†‡0.53 (0.43–0.64)†‡
    ADC (mm2/s)2.43 (2.27–2.59)2.63 (2.52–2.74)3.10 (2.76–3.45)§‡3.24 (2.67–3.81)§
    Fibers (No.)495 (442–548)491 (451–532)368 (273–462)‡372 (236–508)
Body
    FA0.54 (0.49–0.59)0.51 (0.47–0.55)0.46 (0.42–0.51)0.48 (0.41–0.55)
    ADC (mm2/s)2.71 (2.25–3.18)2.71 (2.51–2.92)2.92 (2.51–3.32)3.00 (2.38–3.62)
    Fibers (No.)254 (221–288)221 (199–243)171 (133–210)‡172 (70–275)
Splenium
    FA0.82 (0.79–0.85)0.79 (0.77–0.81)0.70 (0.65–0.75)†0.63 (0.55–0.71)†‖
    ADC (mm2/s)2.24 (2.11–2.37)2.39 (2.29–2.48)2.41 (2.11–2.71)2.58 (2.35–2.81)
    Fibers (No.)937 (815–1058)958 (882–1035)766 (660–873)‡508 (273–744)§‖

  • Note:—DTI indicates diffusion tensor imaging; TBI, traumatic brain injury; FA, fractional anisotropy; ADC, apparent diffusion coefficient.

  • * Values are given as mean (95% confidence intervals).

  • † P < .001, versus control subjects.

  • ‡ P < .05.

  • § P < .01.

  • ‖ P < .001, versus mild TBI.