DTI group results and Mann-Whitney–Wilcoxon test for comparison of mean FA with healthy controls (group Ib)*
| FA | Pyramid | Pons | Peduncle | Capsule | Cent. Semi. | Precent. Gyr. | FA CST | MD CST |
|---|---|---|---|---|---|---|---|---|
| Group IV | ||||||||
| Mean | 456.07 | 489.71 | 593.93 | 570.93 | 426.21 | 356.21 | 510.64 | 901.14 |
| SD | 64.98 | 111.86 | 62.62 | 55.01 | 84.69 | 48.50 | 36.10 | 31.99 |
| MWW | (P = .062) | (P = .001) | (P = .001) | (P < .001) | (P > .05) | (P > .05) | ||
| Group III | ||||||||
| Mean | 508.71 | 553.64 | 617.86 | 612.64 | 435.93 | 417.86 | 510.71 | 932.93 |
| SD | 71.20 | 60.87 | 64.34 | 30.82 | 67.28 | 85.67 | 13.82 | 110.01 |
| MWW | (P > .05) | (P = .022) | (P < .001) | (P = .116) | (P > .05) | (P > .05) | ||
| Group II | ||||||||
| Mean | 498.75 | 531.00 | 582.38 | 643.75 | 475.75 | 449.75 | 525.13 | 888.63 |
| SD | 64.25 | 45.76 | 97.70 | 51.24 | 63.29 | 34.02 | 17.04 | 50.71 |
| Group Ib (controls) | ||||||||
| Mean | 495.32 | 577.29 | 592.06 | 648.34 | 531.66 | 475.09 | 524.25 | 897.10 |
| SD | 63.47 | 66.97 | 65.80 | 48.97 | 53.97 | 50.41 | 24.58 | 34.92 |
Note:—MWW indicates Mann-Whitney–Wilcoxon test; Cent. Semi., centrum semiovale; Precent. Gyr., precentral gyrus; DTI, diffusion tensor imaging; FA, fractional anisotropy.
* The lowest mean FA in comparison with controls is found in the internal capsule, centrum semiovale, and the precentral gyrus of group IV (EE clinically probable/definite) and the internal capsule and centrum semiovale for patients of group III (EE clinically possible). The rightmost FA/MD CST columns illustrate diffusion characteristics averaged for the entire CST. FA ranges from 1000 (maximum anisotropy) to 0 (no anisotropy). MD exhibits statistically significant differences with elevation in the internal capsule in group IV compared with healthy controls (data not shown).