Table 3:

Multivariate analysis of prognostic factors using the Cox proportional hazards model with forward stepwise selection in 180 patients with HGA and spectra obtained at STEa

Variable/ValueNo.Hazard Ratio (95% CI)P
Clinical parameters/treatment<.001
    Conservative support5811.564 (7.242–18.465)
    Radiotherapy alone311.768 (1.100–2.841)
    Chemoradiotherapy911.000
Spectroscopy parameters
Intensity signals normalized to unit-length (NI)
    NI3.67<.001
    <0.0473712.132 (1.504–3.023)
    >0.04731091.000
  • a Age (<50 years vs >50 years), sex, WHO grade, KPS, extent of surgery, the spectroscopic parameters normalized intensity signal at 0.98 ppm, and the ratio between intensity signals at 3.67 and 0.98 ppm were not selected as elective prognostic factors.