Agreement between IPH detected by MR imaging and histology

	Reader		Histology +	Histology −	Total
No. of Images			63	81	144
CE-MRA mask^a	1	+	57	2	59
		−	6	79	85
	2	+	53	0	53
		−	10	81	91
TOF^b	1	+	50	11	61
		−	13	70	83
	2	+	50	10	60
		−	13	71	84

a Reader 1: Sensitivity, specificity, PPV, and NPV (95% CI) are 90% (80%–96%), 98% (91%–100%), 97% (87%–99%), and 93% (85%–97%), respectively. Reader 2: Sensitivity, specificity, PPV, and NPV (95% CI) are 84% (72%–92%), 100% (94%–100%), 100% (92%–100%), and 89% (80%–94%), respectively.
b Reader 1: Sensitivity, specificity, PPV, and NPV (95% CI) are 79% (66%–88%), 86% (77%–93%), 82% (70%–90%), and 84% (74%–91%), respectively. Reader 2: Sensitivity, specificity, PPV, and NPV (95% CI) are 79% (67%–88%), 88% (78%–94%), 83% (71%–91%), and 85% (75%–91%), respectively.