Univariate logistic regression analysis of the predictive value of thalamic volumetry and DTI findings from the GM with and without the thalamus for patients with EDSS scores worsening during 5 years (dependent variable)a
| Independent Variables | Units | OR (95% CI) | PValues |
|---|---|---|---|
| Baseline NTV | 1 mL | 1.25 (0.63–2.45) | .53 |
| Baseline thalamic FA | 0.01 | 0.99 (0.97–1.02) | .57 |
| Baseline thalamic MD | 0.01 mm2/s × 10−3 | 1.02 (0.98–1.06) | .40 |
| Average NTV thalamic volume change | 1% | 1.00 (0.91–1.11) | .94 |
| Average thalamic FA change | 1% | 0.87 (0.77–0.97) | .01 |
| Average thalamic MD change | 1% | 1.04 (0.97–1.11) | .27 |
| Thalamic lesions | n.a. | 1.06 (0.66–1.68) | .82 |
| Change in thalamic lesions | Yes vs no | 2.23 (0.40–12.5) | .36 |
| Baseline GM without the thalami FA | 0.01 | 1.02 (0.99–1.06) | .22 |
| Baseline GM without the thalami MD | 0.01 mm2/s ×10−3 | 1.14 (1.02–1.27) | .019 |
| Average GM without the thalami FA change | 1% | 0.99 (0.93–1.05) | .63 |
| Average GM without the thalami MD change | 1% | 1.03 (0.92–1.15) | .64 |
a See the text for statistical analysis.