No. of Triplets | Disease Duration | Motor UHDRS | Verbal Fluency | Symbol Digit | Stroop | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
R | P | R | P | R | P | R | P | R | P | R | P | |
Volumes | ||||||||||||
NWMV | 0.46 | NS | −0.22 | NS | −0.44 | NS | 0.44 | NS | 0.65 | <.01 | 0.54 | .04 |
NGMV | −0.16 | NS | −0.50 | NS | −0.67 | <.01 | 0.65 | <.01 | 0.41 | NS | 0.40 | NS |
Frontal cortex | −0.40 | NS | −0.60 | .02 | −0.59 | .02 | 0.65 | <.01 | 0.33 | NS | 0.31 | NS |
Parietal cortex | −0.38 | NS | −0.67 | <.01 | −0.60 | .02 | 0.74 | <.01 | 0.37 | NS | 0.37 | NS |
Temporal cortex | −0.32 | NS | −0.45 | NS | −0.62 | .01 | 0.60 | .02 | 0.34 | NS | 0.45 | NS |
Occipital cortex | −0.07 | NS | −0.36 | NS | −0.66 | <.01 | 0.77 | <.001 | 0.61 | .01 | 0.68 | <.01 |
Caudate nuclei | −0.16 | NS | −0.55 | .03 | −0.80 | <.001 | 0.65 | <.01 | 0.53 | .04 | 0.46 | NS |
Putamen | −0.24 | NS | −0.59 | .02 | −0.78 | <.001 | 0.59 | .02 | 0.50 | NS | 0.49 | NS |
Globi pallidi | −0.14 | NS | −0.63 | .01 | −0.79 | <.001 | 0.51 | .0496 | 0.46 | NS | 0.37 | NS |
Thalami | −0.24 | NS | −0.34 | NS | −0.71 | <.01 | 0.57 | .03 | 0.51 | NS | 0.62 | .01 |
MT ratios | ||||||||||||
WM | −0.14 | NS | −0.72 | <.01 | −0.81 | <.001 | 0.73 | <.01 | 0.64 | .01 | 0.64 | .01 |
GM | −0.25 | NS | −0.68 | <.01 | −0.81 | <.001 | 0.88 | <.0001 | 0.57 | .04 | 0.58 | .03 |
Frontal cortex | −0.34 | NS | −0.65 | <.01 | −0.55 | .03 | 0.61 | .02 | 0.26 | NS | 0.23 | NS |
Parietal cortex | −0.26 | NS | −0.66 | <.01 | −0.64 | .01 | 0.63 | .01 | 0.34 | NS | 0.30 | NS |
Temporal cortex | −0.05 | NS | −0.77 | <.001 | −0.77 | <.001 | 0.83 | <.001 | 0.58 | .02 | 0.49 | NS |
Occipital cortex | −0.36 | NS | −0.61 | .02 | −0.71 | <0.01 | 0.74 | <.01 | 0.39 | NS | 0.41 | NS |
Caudate nuclei | 0.02 | NS | −0.60 | .02 | −0.23 | NS | 0.35 | NS | 0.21 | NS | 0.10 | NS |
Putamen | 0.24 | NS | −0.58 | .02 | −0.78 | <.001 | 0.72 | <.01 | 0.81 | <.001 | 0.72 | <.01 |
Globi pallidi | 0.05 | NS | −0.29 | NS | 0.55 | .03 | 0.46 | NS | 0.51 | NS | 0.48 | NS |
Thalami | 0.12 | NS | −0.56 | .03 | −0.30 | NS | 0.30 | NS | 0.22 | NS | 0.09 | NS |
Note:—Bold indicates statistically significant data.