Variably hyperintense brain structures on T2-weighted MRI of 5 infants with known CLD
| Brain Structure | Infant 1 | Infant 2 | Infant 3 | Infant 4 | Infant 5 | Total (%) |
|---|---|---|---|---|---|---|
| Putamen | No | No | Yes (patchy) | No | No | 1 (20) |
| Caudate nuclei | No | No | No | No | Yes (patchy) | 1 (20) |
| Thalami | Yes (patchy) | Yes (patchy) | Yes (patchy) | No | Yes (patchy) | 4 (80) |
| Substantia nigra | No | Yes (patchy) | Yes (mild/patchy) | Yes (patchy) | Yes (mild/patchy) | 4 (80) |
Note:—In all infants, MR imaging demonstrated abnormal signal in the cerebral subcortical white matter, external capsule, extreme capsule, corpus callosum, corticospinal tracts, cerebellum, globus pallidus, midbrain, and pons.