Table 3:

Relationship between in vivo 3T carotid plaque components and recent ipsilateral thromboembolic symptoms for 50 patients with mild/moderate carotid stenosis measured by contrast-enhanced MR angiography

Variable	Symptomatic (n = 6)	Asymptomatic (n = 44)	OR (95% CI)	PValue	AUC
Plaque burden
% wall volume	61.0 ± 5.8	56.1 ± 9.2	1.93 (0.70–5.31)^a	.204	0.689
% stenosis on MRA	50.8 ± 6.9	55.5 ± 9.7	0.61 (0.25–1.46)^a	.265	0.339
Ulceration on MRA	50%	36%	1.75 (0.32–9.72)	.661	0.568
Prevalence plaque components
Fibrous cap thin/ruptured	100%	39%	n/a (2.13-infinity)^b	.006^c	0.807
Lipid-rich necrotic core	100%	43%	n/a (1.77-infinity)^b	.022^c	0.784
Hemorrhage	67%	25%	6.00 (0.96–37.4)	.055	0.708
Calcifications	67%	84%	0.38 (0.06–2.48)	.311	0.413
% Volume of plaque components
Lipid-rich necrotic core	18.5 ± 12.2	6.6 ± 11.3	1.90 (1.03–3.51)^a	.040	0.837
Hemorrhage	6.9 ± 6.6	1.9 ± 5.0	3.22 (0.97–10.71)^a	.056	0.750
Calcifications	2.9 ± 3.7	4.7 ± 5.9	0.44 (0.05–4.02)^a	.470	0.405

a OR and 95% CI for a 10% increase.
b Lower limit CI estimated by exact logistic regression analysis. “n/a” was used because OR cannot be calculated in the presence of zero cells in a 2 × 2 table.
c Fisher exact test.