MTR and D̅ histogram metrics in NABT in healthy volunteers, patients with ADEM, and patients with MS
| Finding | Control Subjects | Patients with ADEM | Patients with MS | P Value | |
|---|---|---|---|---|---|
| Patients with ADEM vs Patients with MS | Control Subjects vs Patients with MS | ||||
| MTR (%) | 40.6 (1.4) | 41.3 (1.24) | 38.6 (1.08) | <.001 | .003 |
| MTR peak height | 117.7 (13.0) | 105.6 (19.2) | 104.4 (14.3) | >.05 | .05 |
| MTR peak position (%) | 35.7 (1.7) | 36.8 (1.5) | 33.2 (1.7) | <.001 | .007 |
| D̅ (× 10−3 mm2/s) | 0.93 (0.05) | 0.92 (0.03) | 0.98 (0.06) | .03 | .009 |
| D̅ peak height | 110.7 (12.5) | 97.3 (19.0) | 89.9 (11.0) | >.05 | <.001 |
| D̅ peak position (× 10−3 mm2/s) | 0.77 (0.04) | 0.75 (0.02) | 0.77 (0.04) | >.05 | >.05 |
Note.—Data are the means; data in parentheses are the SDs. No significant difference between control subjects and patients with ADEM was found.