TABLE

Results of AVM embolization with 2-P-HEMA and evaluation of its properties

Animal	Patent AVM	2-P-HEMA Concentration	Injection Location and Volume (mL)	Injection Speed (mL/mim)	Occlusion of Embolized Nidus Compartment	Complications Detected at Angiography	Postembolization MR Imaging and CT Finding	Time of Follow-Up Angiography and Nidus Occlusion
1	Yes	Pure	PA, 0.6; RA, 0.4	0.1	PA complete, RA complete	None	Partial infarction in right hemisphere, no 2-P-HEMA in brain vessels	At 1 and 8 mo: PA complete, RA complete
2	Yes	Pure	PA, 0.4	0.4	PA complete	Vasospasm	Normal	At 3 mo: complete; at 5 mo: partial recanalization
3	Yes	Pure	PA, 0.7; RA, 0.4	0.1	PA complete, RA complete	None	Normal	At 2 and 7 mo: PA complete, RA complete
4	Yes	Pure	PA, 0.6	0.1	PA complete	None	Normal	At 1 and 6 mo: complete
5	Yes	Pure	PA, 0.5	0.1	PA complete	None	Normal	At 2 and 6 mo: complete
6	Yes	Pure	PA, 0.8	0.1	PA complete	None	Normal	At 1 and 8 mo: complete
7	Yes	50%	PA. 0.6	0.1	PA incomplete	Embolic events	Infarction in right hemisphere, 2-P-HEMA in brain vessels	At 15 h: incomplete

* To make pure 2-P-HEMA, 11% 2-P-HEMA by volume was dissolved in 89% ethenol by volume. To make 50% 2-P-HEMA, 5.5% 2-P-HEMA by volume was dissolved in 79.5% ethanbol boy volume. Sterilized 2-P-HEMA (1 mL) was mixed with tungsten (0.005 g).