Differences in slopes between patients who were younger (≤6.8 years) or older (>6.8 years) at the start of craniospinal irradiation
| CC Region | Age at CSI | Slope* | Significance† |
|---|---|---|---|
| Total | Younger | −24.0 | 0.27 |
| Older | −16.0 | ||
| Rostrum | Younger | −0.6 | 0.24 |
| Older | 1.0 | ||
| Genu | Younger | −4.4 | 0.56 |
| Older | −2.4 | ||
| Rostral body | Younger | −1.8 | 0.92 |
| Older | −2.0 | ||
| Anterior midbody | Younger | −2.2 | 0.42 |
| Older | −1.2 | ||
| Posterior midbody | Younger | −1.4 | 0.97 |
| Older | −1.4 | ||
| Isthmus | Younger | −2.8 | 0.56 |
| Older | −2.0 | ||
| Splenium | Younger | −13.4 | 0.09 |
| Older | −4.8 |
Note.—CC indicates corpus callosum; CSI, craniospinal irradiation.
* Change in CC size per year since start of CSI (mm2).
† Testing H0: slope (reduced) = slope (conventional); P < .05, two-tailed test.