Averaged ADC and FA values for the control subjects and patients
| A: ADC values, mm2/sec | |||
|---|---|---|---|
| ROI | Control Subjects, × 10−6 | Patients, ×10−6 | P Value |
| Internal capsule | 674 ± 81 | 683 ± 59 | .732 |
| Splenium* | 769 ± 61 | 628 ± 74 | .001 |
| Thalamus | 718 ± 60 | 719 ± 62 | .975 |
| Putamen | 677 ± 75 | 707 ± 55 | .184 |
| B: FA values | |||
|---|---|---|---|
| ROI | Control Subjects | Patients | P Value |
| Internal capsule* | 0.725 ± 0.066 | 0.624 ± 0.072 | <.001 |
| Splenium* | 0.808 ± 0.060 | 0.678 ± 0.010 | .002 |
| Thalamus | 0.377 ± 0.075 | 0.401 ± 0.040 | .147 |
| Putamen | 0.286 ± 0.081 | 0.307 ± 0.040 | .257 |
Note.—Table lists the mean ADC and FA values ± SD for all patients and control subjects within the respective ROIs. Left- and right-sided ADC and FA values were averaged. A statistically significant ADC decrease is seen for the splenium, and a statistically significant FA decrease is seen for the internal capsule. A P value of <.005 was considered to indicate a statistically significant difference. Analysis was performed by using a two-tailed Wilcoxon rank sum test.
* Statistically significant difference.