Thresholds beyond which PCT results were significantly different from reference results
| Value and Region | Temporal Sampling Interval (seconds) | |||
|---|---|---|---|---|
| Group 1 (30 mL) | Group 2 (40 mL) | Group 3 (50 mL) | Group 4 (60 mL) | |
| rCBF | ||||
| Healthy hemisphere | 2 | 3 | 3 | 4 |
| Cortical gray matter | 3 | 3 | 4 | 5 |
| White matter | 2 | 3 | 3 | 4 |
| Caudate nucleus | 3 | 4 | 4 | 5 |
| Lenticular nucleus | 2 | 3 | 4 | 4 |
| Ischemic area | 2 | 3 | 3 | 4 |
| Ischemic/healthy ratio | 2 | 3 | 3 | 4 |
| rCBV | ||||
| Healthy hemisphere | 3 | 4 | 4 | 5 |
| Cortical gray matter | 3 | 4 | 5 | 6 |
| White matter | 2 | 3 | 3 | 4 |
| Caudate nucleus | 3 | 3 | 4 | 5 |
| Lenticular nucleus | 3 | 3 | 4 | 5 |
| Ischemic area | 2 | 3 | 3 | 4 |
| Ischemic/healthy ratio | 2 | 3 | 3 | 4 |
| MTT | ||||
| Healthy hemisphere | 3 | 4 | 5 | 6 |
| Cortical gray matter | 4 | 5 | 5 | 6 |
| White matter | 4 | 4 | 5 | 5 |
| Caudate nucleus | 3 | 4 | 5 | 6 |
| Lenticular nucleus | 3 | 4 | 4 | 6 |
| Ischemic area | 3 | 3 | 4 | 5 |
| Ischemic/healthy ratio | 3 | 3 | 4 | 4 |
| TTP | ||||
| Healthy hemisphere | 3 | 4 | 5 | 6 |
| Cortical gray matter | 4 | 5 | 6 | 6 |
| White matter | 3 | 4 | 5 | 6 |
| Caudate nucleus | 2 | 3 | 4 | 5 |
| Lenticular nucleus | 2 | 4 | 4 | 5 |
| Ischemic area | 2 | 3 | 4 | 5 |
| Ischemic/healthy ratio | 2 | 3 | 3 | 4 |
| Global | 2 | 3 | 3 | 4 |
Note.—Reference results were calculated from the raw acquisition PCT series (temporal sampling interval of 1 second). The final global threshold for each volume was defined as the minimum temporal sampling interval identified as accurate for any of the four parametric PCT results in any region.