TABLE 2:

Neonatal and late imaging findings for children who had neonatal thalamic edema with cortical edema

Patient No.Follow-up Age in Months (CT/MR Imaging)Indications Given for Follow-up ImagingNeonatal CT: Cerebellar VermisNeonatal CT: Cerebellar HemispheresFollow-up Imaging: Cerebellar VermisFollow-up Imaging: Cerebellar HemispheresFollow-up Basal Ganglia*Follow-up Cerebral CortexFollow-up Cerebral White Matter
13NA/7Severe HIE, seizuresNormal?EdemaSuperior vermis atrophyNormalThalami, lentiformsRolandicGlobal
14NA/7Neonatal HIE, infantile spasmsNormal?EdemaNormalNormalLentiforms, ?thalamiGlobalGlobal
1513/NASeizuresNormal?EdemaNormalNormalThalami, lentiformsGlobalGlobal
1613/NANANormalEdemaNormalNormalThalamiGlobal asymmetricGlobal asymmetric
175/NABirth asphyxiaNormalNormalNormalNormalThalami, lentiformsGlobalGlobal
18107/NAFollow-up neonatal IVH and infarction?EdemaEdemaNormalNormalThalami, lentiforms asymmetricGlobalGlobal
194/NAFollow-up HIE, developmental delayNormal?EdemaSuperior vermis atrophyNormalThalami, ?lentiformsNormalGlobal
2013/NANANormalNormalNormalNormalThalami, ?lentiformsRolandicGlobal
2115/NASeizures, microcephaly, spastic cerebral palsyNormal?EdemaNormalNormalThalami, lentiformsGlobalGlobal
2280/NADevelopmental delay, seizuresNormalNormalSuperior vermis atrophy?AtrophyAsymmetric thalami, lentiformsAsymmetric Lt global, Rt RolandicAsymmetric Lt global
235/NANANormal?EdemaNormalNormalAsymmetric lentiforms, thalamiAsymmetric globalAsymmetric global
24NA/49Follow-up HIENormalNormalNormalNormalNormalPosteriorPosterior
255/NAFollow-up HIENormalNormalNormalNormalThalami, lentiformsAsymmetric globalAsymmetric global
26NA/25Follow-up neonatal HIE seizuresNormalNormalSuperior vermis atrophy, ?inferior vermis atrophyNormalThalami, lentiformsRolandicGlobal
  • Note.—NA indicates not applicable because procedure not performed; HIE, hypoxic-ischemic encephalopathy; ?, equivocal; IVH, intraventricular hemorrhage; Global, generalized abnormality. Note that anatomic sites as listed under Follow-up Imaging had one or more of the following: atrophy, abnormal MR imaging signal, or abnormal CT attenuation.

  • * Caudate nuclei were not separately assessed.