Metabolite ratios from the posterior cingulate voxel in the 81 subjects, at 1.5 and 3 T
| Ratio | TE | 1.5 T | 3 T | ||||
|---|---|---|---|---|---|---|---|
| Cognitively Normal (n = 41) | MCI (n = 20) | AD (n = 20) | Cognitively Normal (n = 41) | MCI (n = 20) | AD (n = 20) | ||
| NAA/Cr | 135 | 1.77 (1.55–2.10) | 1.69* (1.45–1.80) | 1.65† (1.37–1.9) | 1.53 (1.22–2.15) | 1.49 (1.32–1.81) | 1.47‡ (1.13–1.61) |
| Cho/Cr | 135 | 0.81 (0.53–0.99) | 0.87 (0.72–0.98) | 0.86‡ (0.72–1.06) | 0.70 (0.56–1.01) | 0.68 (0.53–0.83) | 0.66 (0.55–0.81) |
| NAA/Cr | 30 | 1.57 (1.39–1.71) | 1.51 (1.35–1.66) | 1.44† (1.22–1.60) | 1.50 (1.27–1.72) | 1.45 (1.31–2.27) | 1.40‡ (1.23–1.81) |
| Cho/Cr | 30 | 0.64 (0.56–0.77) | 0.68‡ (0.58–0.80) | 0.68‡ (0.56–0.84) | 0.63 (0.48–0.95) | 0.62 (0.53–0.81) | 0.65 (0.49–0.79) |
| MI/Cr | 30 | 0.66 (0.50–0.82) | 0.70‡ (0.59–0.78) | 0.74* (0.51–0.85) | 0.52 (0.38–0.66) | 0.51 (0.36–0.66) | 0.56‡ (0.36–0.73) |
| NAA/MI | 30 | 2.40 (1.88–3.26) | 2.22* (1.96–2.51) | 2.01† (1.48–2.84) | 2.88 (2.29–3.95) | 2.83 (2.02–4.19) | 2.63‡ (1.71–3.89) |
| Glu + Gln/Cr | 30 | – | – | – | 2.03 (1.46–2.62) | 1.91 (1.45–2.28) | 1.84 (1.34–2.46) |
Note.—Data are the median. Numbers in parentheses are the range.
* P < .01 for comparison of ratios in patients with MCI or AD with those of cognitively normal subjects by using the rank sum test.
† P < .001 for comparison of ratios in patients with MCI or AD with those of cognitively normal subjects by using the rank sum test.
‡ P < .05 for comparison of ratios in patients with MCI or AD with those of cognitively normal subjects by using the rank sum test.