Periventricular echogenicity and ventriculomegaly shown on sonograms as predictors of MR imaging-defined white matter abnormalities*
| Relative Risk of WMA (95% CI) | Sensitivity % | Specificity % | Positive Predictive Value % | Negative Predictive Value % | |
|---|---|---|---|---|---|
| Minimal to moderate WMA | |||||
| Periventricular echogenicity | 0.9 | 44 | 50 | 53 | 41 |
| Grade 2–5 on any sonogram | (0.5–1.7) | ||||
| P value | .8 | ||||
| Periventricular echogenicity | 2.0 | 22 | 100 | 100 | 50 |
| Grade 3–5 on any sonogram | (1.4–2.9) | ||||
| P value | .06 | ||||
| Moderate WMA only | |||||
| Periventricular echogenicity | .9 | 38 | 58 | 23 | 74 |
| Grade 2–5 on any sonogram | (0.3–3.0) | ||||
| P value | .8 | ||||
| Periventricular echogenicity | 4.2 | 38 | 96 | 75 | 82 |
| Grade 3–5 on any sonogram | (1.6–11.1) | ||||
| P value | .04 | ||||
| Definite ventriculomegaly on any sonogram | 2.1 | 28 | 100 | 100 | 52 |
| (1.4–3.1) | |||||
| P valuey | .05 |
* Ultrasonography is compared with MR imaging in the absence of an in vivo gold standard of brain injury in the newborn.
Note.—WMA indicates white matter abnormality; CI, confidence interval.