Clinical MR imaging findings
| Finding | Autistic Subjects | Control Subjects | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Normocephaly (n = 26) | Macrocephaly (n = 12) | Normocephaly (n = 19) | Benign Macrocephaly (n = 8) | Reading Disorder (n = 17) | ||||||
| Signal hyperintensity | 4 | (15.4) | 1 | (8.3) | 2 | (10.5) | 2* | (25.0) | 1 | (5.9) |
| Mild atrophy | 2 | (7.7) | - | - | - | - | - | - | - | - |
| Prominent perivascular spaces | 2 | (7.7) | 1 | (8.3) | 1 | (5.3) | 2* | (25.0) | - | - |
| Temporal horn prominence | 1 | (3.8) | 1 | (8.3) | - | - | - | - | 1 | (5.9) |
| Hypothalamic signal abnormality | 1 | (3.8) | - | - | - | - | - | - | ||
| Ventricular asymmetry | - | - | - | - | - | - | - | - | 1 | (5.9) |
| Arachnoid cyst | - | - | - | - | 1 | (5.3) | - | - | 3 | (17.6) |
| Left choroidal fissure cyst | 1 | (3.8) | - | - | - | - | - | - | 1 | (5.9) |
| Possible pineal cyst | 1 | (3.8) | - | - | - | - | - | - | - | - |
Note.—Data are the number of subjects. Numbers in parentheses are percentages.
* One subject with benign macrocephaly had both a signal abnormality and prominent perivascular space noted. No other dual clinical abnormalities were identified in other subjects.