Table 2:

Diagnostic accuracy of imaging and histopathologic parameters in differentiating grade III and IV astrocytomas using hot spot ROIs

Parameters	AUC	95% CI	Cutoff Value	Sensitivity (%)	Specificity (%)
MVA	0.78	0.60–0.90	<2.32	77	73
MVD	0.62	0.44–0.78	<103	95	36
Hot spot Vp_Φ	0.81	0.64–0.92	<1.88	91	73
Hot spot Vp_SI	0.66	0.47–0.81	<4.2	91	64
Hot spot uCBV	0.80	0.63–0.92	<141	86	73
Hot spot rCBV	0.70	0.51–0.85	<9.88	68	73
Hot spot K^trans_Φ	0.78	0.60–0.90	<0.024	86	64
Hot spot K^trans_SI	0.72	0.53–0.86	<0.056	82	64
Combined Vp_Φ + K^trans_Φ + MVA + uCBV	0.85	0.68–0.95	<0.67	77	82