GM regions significantly reduced (P < .05 FDR corrected) in the autistic group by comparison with the controls
| Anatomic Location | Talairach Coordinates Center of Cluster, x y z | Peak of Significance (t score) | Cluster size (No. of voxels) |
|---|---|---|---|
| Basal forebrain, nucleus accumbens | 0 1 −2 | 4.05 | 1282 |
| Supplementary motor area (BA6) | 2 −1 47 | 4.12 | 699 |
| Left insula, left putamen, left perisylvian cortex (BA48) | −43 −2 13 | 5.37 | 6945 |
| Right insula, right putamen, right perisylvian cortex (BA48) | 34 −2 14 | 5.42 | 8266 |
| Left cerebellum | −26 −58 −37 | 5.56 | 6452 |
| Right cerebellum | 23 −55 −39 | 5.29 | 10,441 |
| Left DLPFC (BA47) | −44 15 34 | 4.93 | 1513 |
| Left inferior temporal gyrus (BA20) | −46 −40 −14 | 5.40 | 1708 |
| Left middle temporal gyrus (BA21) and left superior temporal gyrus (BA22) | −56 −19 −2 | 5.96 | 2844 |
| Left precuneus (BA7) | −1 −68 34 | 5.78 | 1225 |
| Left occipito-basal cortex (BA18) | −14 −78 −18 | 5.48 | 359 |
| Left inferior frontal gyrus (BA44) | −39 22 2 | 5.39 | 276 |
| Right postcentral cortex (BA1,2,3), right inferior parietal lobe (BA40) | 41 −33 40 | 5.35 | 1382 |
Note:—All labels are derived from the Anatomical Automatic Atlas. The x, y, z coordinates are the Talairach coordinates of the center of each 3D cluster.43 BAs also are provided.